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A novel region in the Ca(V)2.1 α(1) subunit C-terminus regulates fast synaptic vesicle fusion and vesicle docking at the mammalian presynaptic active zone

In central nervous system (CNS) synapses, action potential-evoked neurotransmitter release is principally mediated by Ca(V)2.1 calcium channels (Ca(V)2.1) and is highly dependent on the physical distance between Ca(V)2.1 and synaptic vesicles (coupling). Although various active zone proteins are pro...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Lübbert, Matthias, Goral, R Oliver, Satterfield, Rachel, Putzke, Travis, van den Maagdenberg, Arn MJM, Kamasawa, Naomi, Young, Samuel M
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548488/
https://ncbi.nlm.nih.gov/pubmed/28786379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28412
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