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The docking of synaptic vesicles on the presynaptic membrane induced by α-synuclein is modulated by lipid composition

α-Synuclein (αS) is a presynaptic disordered protein whose aberrant aggregation is associated with Parkinson’s disease. The functional role of αS is still debated, although it has been involved in the regulation of neurotransmitter release via the interaction with synaptic vesicles (SVs). We report...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Nat Commun
Κύριοι συγγραφείς: Man, Wing K., Tahirbegi, Bogachan, Vrettas, Michail D., Preet, Swapan, Ying, Liming, Vendruscolo, Michele, De Simone, Alfonso, Fusco, Giuliana
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group UK 2021
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876145/
https://ncbi.nlm.nih.gov/pubmed/33568632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21027-4
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