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The docking of synaptic vesicles on the presynaptic membrane induced by α-synuclein is modulated by lipid composition

α-Synuclein (αS) is a presynaptic disordered protein whose aberrant aggregation is associated with Parkinson’s disease. The functional role of αS is still debated, although it has been involved in the regulation of neurotransmitter release via the interaction with synaptic vesicles (SVs). We report...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Man, Wing K., Tahirbegi, Bogachan, Vrettas, Michail D., Preet, Swapan, Ying, Liming, Vendruscolo, Michele, De Simone, Alfonso, Fusco, Giuliana
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876145/
https://ncbi.nlm.nih.gov/pubmed/33568632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21027-4
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