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A Role of Cholesterol in Modulating the Binding of α-Synuclein to Synaptic-Like Vesicles

α-Synuclein (αS) is a presynaptic protein whose aggregation is associated with Parkinson’s disease (PD). Although the physiological function of αS is still unclear, several lines of evidence indicate that this protein may play a role in the trafficking of synaptic vesicles (SVs) during neurotransmit...

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Detalles Bibliográficos
Publicado en:Front Neurosci
Autores principales: Man, Wing K., De Simone, Alfonso, Barritt, Joseph D., Vendruscolo, Michele, Dobson, Christopher M., Fusco, Giuliana
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000551/
https://ncbi.nlm.nih.gov/pubmed/32063829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00018
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