Ca(V)2.1 α(1) Subunit Expression Regulates Presynaptic Ca(V)2.1 Abundance and Synaptic Strength at a Central Synapse

The abundance of presynaptic Ca(V)2 voltage-gated Ca(2+) channels (Ca(V)2) at mammalian active zones (AZs) regulates the efficacy of synaptic transmission. It is proposed that presynaptic Ca(V)2 levels are saturated in AZs due to a finite number of slots that set Ca(V)2 subtype abundance and that Ca...

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Vydáno v:Neuron
Hlavní autoři: Lübbert, Matthias, Goral, R. Oliver, Keine, Christian, Thomas, Connon, Guerrero-Given, Debbie, Putzke, Travis, Satterfield, Rachel, Kamasawa, Naomi, Young, Samuel M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413316/
https://ncbi.nlm.nih.gov/pubmed/30545599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.11.028
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