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A novel region in the Ca(V)2.1 α(1) subunit C-terminus regulates fast synaptic vesicle fusion and vesicle docking at the mammalian presynaptic active zone
In central nervous system (CNS) synapses, action potential-evoked neurotransmitter release is principally mediated by Ca(V)2.1 calcium channels (Ca(V)2.1) and is highly dependent on the physical distance between Ca(V)2.1 and synaptic vesicles (coupling). Although various active zone proteins are pro...
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| Publicado en: | eLife |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
eLife Sciences Publications, Ltd
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5548488/ https://ncbi.nlm.nih.gov/pubmed/28786379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28412 |
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