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Molecular Origins of the Compatibility between Glycosaminoglycans and Aβ40 Amyloid Fibrils
The Aβ peptide forms extracellular plaques associated with Alzheimer's disease. In addition to protein fibrils, amyloid plaques also contain non-proteinaceous components, including glycosaminoglycans (GAGs). We have shown previously that the GAG low-molecular-weight heparin (LMWH) binds to Aβ40...
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| Опубликовано в: : | J Mol Biol |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5548265/ https://ncbi.nlm.nih.gov/pubmed/28697887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.07.003 |
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