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Molecular Origins of the Compatibility between Glycosaminoglycans and Aβ40 Amyloid Fibrils

The Aβ peptide forms extracellular plaques associated with Alzheimer's disease. In addition to protein fibrils, amyloid plaques also contain non-proteinaceous components, including glycosaminoglycans (GAGs). We have shown previously that the GAG low-molecular-weight heparin (LMWH) binds to Aβ40...

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Detaylı Bibliyografya
Yayımlandı:J Mol Biol
Asıl Yazarlar: Stewart, Katie L., Hughes, Eleri, Yates, Edwin A., Middleton, David A., Radford, Sheena E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548265/
https://ncbi.nlm.nih.gov/pubmed/28697887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.07.003
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