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Comparative Effects of Ions, Molecular Crowding, and Bulk DNA on the Damage Search Mechanisms of hOGG1 and hUNG()

The energetic nature of the interactions of DNA base excision repair glycosylases with undamaged and damaged DNA and the nuclear environment are expected to significantly impact the time it takes for these enzymes to search for damaged DNA bases. In particular, the high concentration of monovalent i...

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Pubblicato in:Biochemistry
Autori principali: Cravens, Shannen L., Stivers, James T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548102/
https://ncbi.nlm.nih.gov/pubmed/27571472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00482
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