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Comparative Effects of Ions, Molecular Crowding, and Bulk DNA on the Damage Search Mechanisms of hOGG1 and hUNG()

The energetic nature of the interactions of DNA base excision repair glycosylases with undamaged and damaged DNA and the nuclear environment are expected to significantly impact the time it takes for these enzymes to search for damaged DNA bases. In particular, the high concentration of monovalent i...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Cravens, Shannen L., Stivers, James T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548102/
https://ncbi.nlm.nih.gov/pubmed/27571472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00482
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