A carregar...
APE1 Accelerates Turnover of hOGG1 by Preventing Retrograde Binding to the Abasic Site Product
A major product of oxidative DNA damage is 8-oxoguanine. In humans, 8-oxoguanine DNA Glycosylase (hOGG1) facilitates removal of these lesions, producing an abasic (AP) site in the DNA that is subsequently incised by AP-endonuclease 1 (APE1). APE1 stimulates turnover of several glycosylases by accele...
Na minha lista:
| Publicado no: | Biochemistry |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5526596/ https://ncbi.nlm.nih.gov/pubmed/28345889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00017 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|