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Electrostatic Properties of Complexes along a DNA Glycosylase Damage Search Pathway

[Image: see text] Human uracil DNA glycosylase (hUNG) follows an extended reaction coordinate for locating rare uracil bases in genomic DNA. This process begins with diffusion-controlled engagement of undamaged DNA, followed by a damage search step in which the enzyme remains loosely associated with...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Cravens, Shannen L., Hobson, Matthew, Stivers, James T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263432/
https://ncbi.nlm.nih.gov/pubmed/25408964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi501011m
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