טוען...

Comparison of the protein–protein interfaces in the p53–DNA crystal structures: Towards elucidation of the biological interface

p53, the tumor suppressor protein, functions as a dimer of dimers. However, how the tetramer binds to the DNA is still an open question. In the crystal structure, three copies of the p53 monomers (containing chains A, B, and C) were crystallized with the DNA-consensus element. Although the structure...

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מידע ביבליוגרפי
Main Authors: Ma, Buyong, Pan, Yongping, Gunasekaran, K., Venkataraghavan, R. Babu, Levine, Arnold J., Nussinov, Ruth
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2005
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC554805/
https://ncbi.nlm.nih.gov/pubmed/15738397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500215102
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