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Dipeptide analysis of p53 mutations and evolution of p53 family proteins()

p53 gain-of-function mutations are similar to driver mutations in cancer genes, with both promoting tumorigenesis. Most previous studies focused on residues lost by mutations, providing information related to a dominantly-negative effect. However, to understand gain-of-function mutations, it is also...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Huang, Qiang, Yu, Long, Levine, Arnold J., Nussinov, Ruth, Ma, Buyong
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429922/
https://ncbi.nlm.nih.gov/pubmed/23583620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2013.04.002
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