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Lysine120 Interactions with p53 Response Elements can Allosterically Direct p53 Organization

p53 can serve as a paradigm in studies aiming to figure out how allosteric perturbations in transcription factors (TFs) triggered by small changes in DNA response element (RE) sequences, can spell selectivity in co-factor recruitment. p53-REs are 20-base pair (bp) DNA segments specifying diverse fun...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Pan, Yongping, Nussinov, Ruth
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916859/
https://ncbi.nlm.nih.gov/pubmed/20700496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000878
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