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The Role of Response Elements Organization in Transcription Factor Selectivity: The IFN-β Enhanceosome Example

What is the mechanism through which transcription factors (TFs) assemble specifically along the enhancer DNA? The IFN-β enhanceosome provides a good model system: it is small; its components' crystal structures are available; and there are biochemical and cellular data. In the IFN-β enhanceosom...

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Autors principals: Pan, Yongping, Nussinov, Ruth
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116919/
https://ncbi.nlm.nih.gov/pubmed/21698143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002077
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