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The Role of Response Elements Organization in Transcription Factor Selectivity: The IFN-β Enhanceosome Example

What is the mechanism through which transcription factors (TFs) assemble specifically along the enhancer DNA? The IFN-β enhanceosome provides a good model system: it is small; its components' crystal structures are available; and there are biochemical and cellular data. In the IFN-β enhanceosom...

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Hlavní autoři: Pan, Yongping, Nussinov, Ruth
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116919/
https://ncbi.nlm.nih.gov/pubmed/21698143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002077
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