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Mechanisms of transcription factor selectivity

The initiation of transcription is regulated by transcription factors (TFs) binding to DNA response elements (REs). How do TFs recognize specific binding sites among the many similar ones available in the genome? Recent research has illustrated that even a single nucleotide substitution can alter th...

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Detalhes bibliográficos
Publicado no:Trends Genet
Main Authors: Pan, Yongping, Tsai, Chung-Jung, Ma, Buyong, Nussinov, Ruth
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316385/
https://ncbi.nlm.nih.gov/pubmed/20074831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2009.12.003
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