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Lysine120 Interactions with p53 Response Elements can Allosterically Direct p53 Organization
p53 can serve as a paradigm in studies aiming to figure out how allosteric perturbations in transcription factors (TFs) triggered by small changes in DNA response element (RE) sequences, can spell selectivity in co-factor recruitment. p53-REs are 20-base pair (bp) DNA segments specifying diverse fun...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2916859/ https://ncbi.nlm.nih.gov/pubmed/20700496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000878 |
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