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Progressive Neuronal Activation Accompanies Epileptogenesis Caused by Hippocampal Glutamine Synthetase Inhibition

Loss of glutamine synthetase (GS) in hippocampal astrocytes has been implicated in the causation of human mesial temporal lobe epilepsy (MTLE). However, the mechanism by which the deficiency in GS leads to epilepsy is incompletely understood. Here we ask how hippocampal GS inhibition affects seizure...

詳細記述

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書誌詳細
出版年:Exp Neurol
主要な著者: Albright, Benjamin, Dhaher, Roni, Wang, Helen, Harb, Roa, Lee, Tih-Shih W., Zaveri, Hitten, Eid, Tore
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547560/
https://ncbi.nlm.nih.gov/pubmed/27769717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2016.10.007
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