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Progressive Neuronal Activation Accompanies Epileptogenesis Caused by Hippocampal Glutamine Synthetase Inhibition
Loss of glutamine synthetase (GS) in hippocampal astrocytes has been implicated in the causation of human mesial temporal lobe epilepsy (MTLE). However, the mechanism by which the deficiency in GS leads to epilepsy is incompletely understood. Here we ask how hippocampal GS inhibition affects seizure...
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Publicado no: | Exp Neurol |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5547560/ https://ncbi.nlm.nih.gov/pubmed/27769717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2016.10.007 |
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