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Roles of Glutamine Synthetase Inhibition in Epilepsy
Glutamine synthetase (GS, E.C. 6.3.1.2) is a ubiquitous and highly compartmentalized enzyme that is critically involved in several metabolic pathways in the brain, including the glutamine-glutamate-GABA cycle and detoxification of ammonia. GS is normally localized to the cytoplasm of most astrocytes...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3731630/ https://ncbi.nlm.nih.gov/pubmed/22488332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-012-0766-5 |
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