Epigenetic modifiers upregulate MHC II and impede ovarian cancer tumor growth

Expression of MHC class II pathway proteins in ovarian cancer correlates with prolonged survival. Murine and human ovarian cancer cells were treated with epigenetic modulators – histone deacetylase inhibitors and a DNA methyltransferase inhibitor. mRNA and protein expression of the MHC II pathway we...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Turner, Taylor B, Meza-Perez, Selene, Londoño, Angelina, Katre, Ashwini, Peabody, Jacelyn E., Smith, Haller J., Forero, Andres, Norian, Lyse A, Straughn, J. Michael, Buchsbaum, Donald J., Rand all, Troy D., Arend, Rebecca C.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546470/
https://ncbi.nlm.nih.gov/pubmed/28498806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17395
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