The expression of MHC class II molecules on murine breast tumors delays T-cell exhaustion, expands the T-cell repertoire, and slows tumor growth

The expression of MHC class II molecules (MHCII) on tumor cells correlates with survival and responsiveness to immunotherapy. However, the mechanisms underlying these observations are poorly defined. Using a murine breast tumor line, we showed that MHCII-expressing tumors grew more slowly than contr...

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Bibliografische gegevens
Gepubliceerd in:Cancer Immunol Immunother
Hoofdauteurs: McCaw, Tyler R., Li, Mei, Starenki, Dmytro, Cooper, Sara J., Liu, Mingyong, Meza-Perez, Selene, Arend, Rebecca C., Buchsbaum, Donald J., Forero, Andres, Randall, Troy D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Berlin Heidelberg 2018
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504180/
https://ncbi.nlm.nih.gov/pubmed/30334128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-018-2262-5
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