The expression of MHC class II molecules on murine breast tumors delays T-cell exhaustion, expands the T-cell repertoire, and slows tumor growth

The expression of MHC class II molecules (MHCII) on tumor cells correlates with survival and responsiveness to immunotherapy. However, the mechanisms underlying these observations are poorly defined. Using a murine breast tumor line, we showed that MHCII-expressing tumors grew more slowly than contr...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Immunother
Main Authors: McCaw, Tyler R., Li, Mei, Starenki, Dmytro, Cooper, Sara J., Liu, Mingyong, Meza-Perez, Selene, Arend, Rebecca C., Buchsbaum, Donald J., Forero, Andres, Randall, Troy D.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504180/
https://ncbi.nlm.nih.gov/pubmed/30334128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-018-2262-5
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