The expression of MHC class II molecules on murine breast tumors delays T-cell exhaustion, expands the T-cell repertoire, and slows tumor growth

The expression of MHC class II molecules (MHCII) on tumor cells correlates with survival and responsiveness to immunotherapy. However, the mechanisms underlying these observations are poorly defined. Using a murine breast tumor line, we showed that MHCII-expressing tumors grew more slowly than contr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Immunol Immunother
Prif Awduron: McCaw, Tyler R., Li, Mei, Starenki, Dmytro, Cooper, Sara J., Liu, Mingyong, Meza-Perez, Selene, Arend, Rebecca C., Buchsbaum, Donald J., Forero, Andres, Randall, Troy D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer Berlin Heidelberg 2018
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504180/
https://ncbi.nlm.nih.gov/pubmed/30334128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-018-2262-5
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