載入...

Histone deacetylase inhibition promotes intratumoral CD8(+) T-cell responses, sensitizing murine breast tumors to anti-PD1

Histone deacetylase (HDAC) inhibitors impair tumor cell proliferation and alter gene expression. However, the impact of these changes on anti-tumor immunity is poorly understood. Here, we showed that the class I HDAC inhibitor, entinostat (ENT), promoted the expression of immune-modulatory molecules...

全面介紹

Na minha lista:
書目詳細資料
發表在:Cancer Immunol Immunother
Main Authors: McCaw, Tyler R., Li, Mei, Starenki, Dmytro, Liu, Mingyong, Cooper, Sara J., Arend, Rebecca C., Forero, Andres, Buchsbaum, Donald J., Randall, Troy D.
格式: Artigo
語言:Inglês
出版: Springer Berlin Heidelberg 2019
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879872/
https://ncbi.nlm.nih.gov/pubmed/31720815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-019-02430-9
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!