Class I histone deacetylase inhibition promotes CD8 T cell activation in ovarian cancer

OBJECTIVE: Patients with epithelial ovarian cancer (EOC) typically present with late‐stage disease, posing a significant challenge to treatment. Although taxane and platinum‐based chemotherapy plus surgical debulking are initially effective, EOC is marked by frequent recurrence with resistant diseas...

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Publicat a:Cancer Med
Autors principals: McCaw, Tyler R., Goel, Nidhi, Brooke, Dewey J., Katre, Ashwini A., Londoño, Angelina I., Smith, Haller J., Randall, Troy D., Arend, Rebecca C.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Cancer Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7877343/
https://ncbi.nlm.nih.gov/pubmed/33369199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3337
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