Class I histone deacetylase inhibition promotes CD8 T cell activation in ovarian cancer

OBJECTIVE: Patients with epithelial ovarian cancer (EOC) typically present with late‐stage disease, posing a significant challenge to treatment. Although taxane and platinum‐based chemotherapy plus surgical debulking are initially effective, EOC is marked by frequent recurrence with resistant diseas...

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Publicado en:Cancer Med
Autores principales: McCaw, Tyler R., Goel, Nidhi, Brooke, Dewey J., Katre, Ashwini A., Londoño, Angelina I., Smith, Haller J., Randall, Troy D., Arend, Rebecca C.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
Materias:
Cancer Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7877343/
https://ncbi.nlm.nih.gov/pubmed/33369199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3337
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