The expression of MHC class II molecules on murine breast tumors delays T-cell exhaustion, expands the T-cell repertoire, and slows tumor growth

The expression of MHC class II molecules (MHCII) on tumor cells correlates with survival and responsiveness to immunotherapy. However, the mechanisms underlying these observations are poorly defined. Using a murine breast tumor line, we showed that MHCII-expressing tumors grew more slowly than contr...

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Detaylı Bibliyografya
Yayımlandı:Cancer Immunol Immunother
Asıl Yazarlar: McCaw, Tyler R., Li, Mei, Starenki, Dmytro, Cooper, Sara J., Liu, Mingyong, Meza-Perez, Selene, Arend, Rebecca C., Buchsbaum, Donald J., Forero, Andres, Randall, Troy D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Berlin Heidelberg 2018
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504180/
https://ncbi.nlm.nih.gov/pubmed/30334128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-018-2262-5
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