Epigenetic modifiers upregulate MHC II and impede ovarian cancer tumor growth

Expression of MHC class II pathway proteins in ovarian cancer correlates with prolonged survival. Murine and human ovarian cancer cells were treated with epigenetic modulators – histone deacetylase inhibitors and a DNA methyltransferase inhibitor. mRNA and protein expression of the MHC II pathway we...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Turner, Taylor B, Meza-Perez, Selene, Londoño, Angelina, Katre, Ashwini, Peabody, Jacelyn E., Smith, Haller J., Forero, Andres, Norian, Lyse A, Straughn, J. Michael, Buchsbaum, Donald J., Rand all, Troy D., Arend, Rebecca C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546470/
https://ncbi.nlm.nih.gov/pubmed/28498806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17395
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