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Epigenetic modifiers upregulate MHC II and impede ovarian cancer tumor growth

Expression of MHC class II pathway proteins in ovarian cancer correlates with prolonged survival. Murine and human ovarian cancer cells were treated with epigenetic modulators – histone deacetylase inhibitors and a DNA methyltransferase inhibitor. mRNA and protein expression of the MHC II pathway we...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Turner, Taylor B, Meza-Perez, Selene, Londoño, Angelina, Katre, Ashwini, Peabody, Jacelyn E., Smith, Haller J., Forero, Andres, Norian, Lyse A, Straughn, J. Michael, Buchsbaum, Donald J., Rand all, Troy D., Arend, Rebecca C.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546470/
https://ncbi.nlm.nih.gov/pubmed/28498806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17395
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