Tumor suppressor BLU promotes TRAIL-induced apoptosis by downregulating NF-κB signaling in nasopharyngeal carcinoma

A putative tumor suppressor BLU mapped on the chromosomal 3p21 region, is frequently lost in human tumors including nasopharyngeal carcinoma (NPC). To explore the underlying mechanism of tumor suppression by BLU, its potential to promote apoptosis induced by TRAIL, an effector molecule elaborated by...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Zhou, Jiahui, Huang, Zunnan, Wang, Ziyou, Liu, Shumin, Grandien, Alf, Ernberg, Ingemar, He, Zhiwei, Zhang, Xiangning
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546445/
https://ncbi.nlm.nih.gov/pubmed/28029652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14126
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