Tumor suppressor BLU promotes TRAIL-induced apoptosis by downregulating NF-κB signaling in nasopharyngeal carcinoma

A putative tumor suppressor BLU mapped on the chromosomal 3p21 region, is frequently lost in human tumors including nasopharyngeal carcinoma (NPC). To explore the underlying mechanism of tumor suppression by BLU, its potential to promote apoptosis induced by TRAIL, an effector molecule elaborated by...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhou, Jiahui, Huang, Zunnan, Wang, Ziyou, Liu, Shumin, Grandien, Alf, Ernberg, Ingemar, He, Zhiwei, Zhang, Xiangning
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546445/
https://ncbi.nlm.nih.gov/pubmed/28029652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14126
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