Tumor suppressor BLU inhibits proliferation of nasopharyngeal carcinoma cells by regulation of cell cycle, c-Jun N-terminal kinase and the cyclin D1 promoter

BACKGROUND: Tumor suppressor genes function to regulate and block tumor cell proliferation. To explore the mechanisms underlying the tumor suppression of BLU/ZMYND10 gene on a frequently lost human chromosomal region, an adenoviral vector with BLU cDNA insert was constructed. METHODS: BLU was re-exp...

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Bibliographic Details
Main Authors: Zhang, Xiangning, Liu, Hui, Li, Binbin, Huang, Peichun, Shao, Jianyong, He, Zhiwei
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585814/
https://ncbi.nlm.nih.gov/pubmed/22727408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-267
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