Mitogen- and stress-activated Kinase 1 mediates Epstein-Barr virus latent membrane protein 1-promoted cell transformation in nasopharyngeal carcinoma through its induction of Fra-1 and c-Jun genes

BACKGROUND: Mitogen- and Stress-Activated Kinase 1 (MSK1) is a nuclear kinase that serves as active link between extracellular signals and the primary response of gene expression. However, the involvement of MSK1 in malignant transformation and cancer development is not well understood. In this stud...

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Publicat a:BMC Cancer
Autors principals: Li, Binbin, Wan, Zheng, Huang, Guoliang, Huang, Zunnan, Zhang, Xiangning, Liao, Dan, Luo, Shengqun, He, Zhiwei
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434874/
https://ncbi.nlm.nih.gov/pubmed/25958199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1398-3
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