Therapeutic Evaluation of Epstein-Barr Virus-encoded Latent Membrane Protein-1 Targeted DNAzyme for Treating of Nasopharyngeal Carcinomas

The ability of the 10–23 DNAzyme to specifically cleave RNA with high efficiency has fuelled expectation that this agent may have useful applications for targeted therapy. Here, we, for the first time, investigated the antitumor and radiosensitizing effects of a DNAzyme (DZ1) targeted to the Epstein...

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Main Authors: Cao, Ya, Yang, Lifang, Jiang, Wuzhong, Wang, Xiaoyi, Liao, Weihua, Tan, Guolin, Liao, Yuping, Qiu, Yuanzheng, Feng, Deyun, Tang, Faqing, Hou, Bob L, Zhang, Ling, Fu, Jia, He, Fengjiao, Liu, Xiaoyu, Jiang, Wenjuan, Yang, Tubao, Sun, Lun-Quan
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
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Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916047/
https://ncbi.nlm.nih.gov/pubmed/24322331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.257
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