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Krox-20 inhibits Jun-NH(2)-terminal kinase/c-Jun to control Schwann cell proliferation and death
The transcription factor Krox-20 controls Schwann cell myelination. Schwann cells in Krox-20 null mice fail to myelinate, and unlike myelinating Schwann cells, continue to proliferate and are susceptible to death. We find that enforced Krox-20 expression in Schwann cells cell-autonomously inactivate...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172235/ https://ncbi.nlm.nih.gov/pubmed/14757751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200307132 |
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