Tumor suppressor BLU promotes TRAIL-induced apoptosis by downregulating NF-κB signaling in nasopharyngeal carcinoma

A putative tumor suppressor BLU mapped on the chromosomal 3p21 region, is frequently lost in human tumors including nasopharyngeal carcinoma (NPC). To explore the underlying mechanism of tumor suppression by BLU, its potential to promote apoptosis induced by TRAIL, an effector molecule elaborated by...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Zhou, Jiahui, Huang, Zunnan, Wang, Ziyou, Liu, Shumin, Grandien, Alf, Ernberg, Ingemar, He, Zhiwei, Zhang, Xiangning
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546445/
https://ncbi.nlm.nih.gov/pubmed/28029652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14126
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