Lack of β, β-carotene -9’, 10’-oxygenase 2 leads to hepatic mitochondrial dysfunction and cellular oxidative stress in mice

SCOPE: β,β-carotene-9’,10’-dioxygenase 2 (BCO2) is a carotenoid cleavage enzyme localized to the inner mitochondrial membrane in mammals. This study was aimed to assess the impact of genetic ablation of BCO2 on hepatic oxidative stress through mitochondrial function in mice. METHODS AND RESULTS: Liv...

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Bibliografiske detaljer
Udgivet i:	Mol Nutr Food Res
Main Authors:	Wu, Lei, Guo, Xin, Hartson, Steven D., Davis, Mary Abby, He, Hui, Medeiros, Denis M., Wang, Weiqun, Clarke, Stephen L., Lucas, Edralin, Smith, Brenda J., von Lintig, Johannes, Lin, Dingbo
Format:	Artigo
Sprog:	Inglês
Udgivet:	2017
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5546151/ https://ncbi.nlm.nih.gov/pubmed/27991717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201600576
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Lack of β, β-carotene -9’, 10’-oxygenase 2 leads to hepatic mitochondrial dysfunction and cellular oxidative stress in mice

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