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Lack of β, β-carotene -9’, 10’-oxygenase 2 leads to hepatic mitochondrial dysfunction and cellular oxidative stress in mice

SCOPE: β,β-carotene-9’,10’-dioxygenase 2 (BCO2) is a carotenoid cleavage enzyme localized to the inner mitochondrial membrane in mammals. This study was aimed to assess the impact of genetic ablation of BCO2 on hepatic oxidative stress through mitochondrial function in mice. METHODS AND RESULTS: Liv...

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Bibliografski detalji
Izdano u:Mol Nutr Food Res
Glavni autori: Wu, Lei, Guo, Xin, Hartson, Steven D., Davis, Mary Abby, He, Hui, Medeiros, Denis M., Wang, Weiqun, Clarke, Stephen L., Lucas, Edralin, Smith, Brenda J., von Lintig, Johannes, Lin, Dingbo
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546151/
https://ncbi.nlm.nih.gov/pubmed/27991717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201600576
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