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β-carotene oxygenase 2 deficiency-triggered mitochondrial oxidative stress promotes low-grade inflammation and metabolic dysfunction
Low-grade inflammation is a critical pathological factor contributing to the development of metabolic disorders. β-carotene oxygenase 2 (BCO2) was initially identified as an enzyme catalyzing carotenoids in the inner mitochondrial membrane. Mutations in BCO2 are associated with inflammation and meta...
Zapisane w:
| Wydane w: | Free Radic Biol Med |
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| Główni autorzy: | , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2021
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7946548/ https://ncbi.nlm.nih.gov/pubmed/33453359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2021.01.003 |
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