Loss of CDKL5 in Glutamatergic Neurons Disrupts Hippocampal Microcircuitry and Leads to Memory Impairment in Mice

Cyclin-dependent kinase-like 5 (CDKL5) deficiency is a neurodevelopmental disorder characterized by epileptic seizures, severe intellectual disability, and autistic features. Mice lacking CDKL5 display multiple behavioral abnormalities reminiscent of the disorder, but the cellular origins of these p...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Tang, Sheng, Wang, I-Ting Judy, Yue, Cuiyong, Takano, Hajime, Terzic, Barbara, Pance, Katarina, Lee, Jun Y., Cui, Yue, Coulter, Douglas A., Zhou, Zhaolan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2017
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546111/
https://ncbi.nlm.nih.gov/pubmed/28674172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0539-17.2017
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge