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Ion-pulling simulations provide insights into the mechanisms of channel opening of the skeletal muscle ryanodine receptor

The type 1 ryanodine receptor (RyR1) mediates Ca(2+) release from the sarcoplasmic reticulum to initiate skeletal muscle contraction and is associated with muscle diseases, malignant hyperthermia, and central core disease. To better understand RyR1 channel function, we investigated the molecular mec...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Mowrey, David D., Xu, Le, Mei, Yingwu, Pasek, Daniel A., Meissner, Gerhard, Dokholyan, Nikolay V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546034/
https://ncbi.nlm.nih.gov/pubmed/28584051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.760199
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