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Ion-pulling simulations provide insights into the mechanisms of channel opening of the skeletal muscle ryanodine receptor
The type 1 ryanodine receptor (RyR1) mediates Ca(2+) release from the sarcoplasmic reticulum to initiate skeletal muscle contraction and is associated with muscle diseases, malignant hyperthermia, and central core disease. To better understand RyR1 channel function, we investigated the molecular mec...
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| Publicat a: | J Biol Chem |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5546034/ https://ncbi.nlm.nih.gov/pubmed/28584051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.760199 |
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