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Structural Determinants of Skeletal Muscle Ryanodine Receptor Gating
Ryanodine receptor type 1 (RyR1) releases Ca(2+) from intracellular stores upon nerve impulse to trigger skeletal muscle contraction. Effector binding at the cytoplasmic domain tightly controls gating of the pore domain of RyR1 to release Ca(2+). However, the molecular mechanism that links effector...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3585052/ https://ncbi.nlm.nih.gov/pubmed/23319589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.433789 |
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