Lanean...

Ca(2+)-mediated activation of the skeletal-muscle ryanodine receptor ion channel

Cryo-electron micrograph studies recently have identified a Ca(2+)-binding site in the 2,200-kDa ryanodine receptor ion channel (RyR1) in skeletal muscle. To clarify the role of this site in regulating RyR1 activity, here we applied mutational, electrophysiological, and computational methods. Three...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Xu, Le, Chirasani, Venkat R., Carter, Jordan S., Pasek, Daniel A., Dokholyan, Nikolay V., Yamaguchi, Naohiro, Meissner, Gerhard
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302159/
https://ncbi.nlm.nih.gov/pubmed/30341173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004453
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!