Ex-vivo models of the Retinal Pigment Epithelium (RPE) in long-term culture faithfully recapitulate key structural and physiological features of native RPE

The Retinal Pigment Epithelium (RPE) forms the primary site of pathology in several blinding retinopathies. RPE cultures are being continuously refined so that dynamic disease processes in this important monolayer can be faithfully studied outside the eye over longer periods. The RPE substrate, whic...

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Veröffentlicht in:Tissue Cell
Hauptverfasser: Lynn, Savannah A., Ward, Gareth, Keeling, Eloise, Scott, Jenny A., Cree, Angela J., Johnston, David A., Page, Anton, Cuan-Urquizo, Enrique, Bhaskar, Atul, Grossel, Martin C., Tumbarello, David A., Newman, Tracey A., Lotery, Andrew J., Ratnayaka, J. Arjuna
Format: Artigo
Sprache:Inglês
Veröffentlicht: Churchill Livingstone 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545183/
https://ncbi.nlm.nih.gov/pubmed/28669519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tice.2017.06.003
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