Impaired Cargo Clearance in the Retinal Pigment Epithelium (RPE) Underlies Irreversible Blinding Diseases

Chronic degeneration of the Retinal Pigment Epithelium (RPE) is a precursor to pathological changes in the outer retina. The RPE monolayer, which lies beneath the neuroretina, daily internalises and digests large volumes of spent photoreceptor outer segments. Impaired cargo handling and processing i...

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Dettagli Bibliografici
Pubblicato in:Cells
Autori principali: Keeling, Eloise, Lotery, Andrew J., Tumbarello, David A., Ratnayaka, J. Arjuna
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850104/
https://ncbi.nlm.nih.gov/pubmed/29473871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells7020016
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