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Impaired Cargo Clearance in the Retinal Pigment Epithelium (RPE) Underlies Irreversible Blinding Diseases

Chronic degeneration of the Retinal Pigment Epithelium (RPE) is a precursor to pathological changes in the outer retina. The RPE monolayer, which lies beneath the neuroretina, daily internalises and digests large volumes of spent photoreceptor outer segments. Impaired cargo handling and processing i...

詳細記述

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書誌詳細
出版年:Cells
主要な著者: Keeling, Eloise, Lotery, Andrew J., Tumbarello, David A., Ratnayaka, J. Arjuna
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850104/
https://ncbi.nlm.nih.gov/pubmed/29473871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells7020016
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