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Rationalization of a nanoparticle-based nicotine nanovaccine as an effective next-generation nicotine vaccine: a focus on hapten localization

A lipid-polymeric hybrid nanoparticle-based next-generation nicotine nanovaccine was rationalized in this study to combat nicotine addiction. A series of nanovaccines, which had nicotine-haptens localized on carrier protein (LPKN), nanoparticle surface (LPNK), or both (LPNKN), were designed to study...

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Bibliografske podrobnosti
izdano v:Biomaterials
Main Authors: Zhao, Zongmin, Hu, Yun, Harmon, Theresa, Pentel, Paul, Ehrich, Marion, Zhang, Chenming
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544940/
https://ncbi.nlm.nih.gov/pubmed/28551462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2017.05.031
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