Engineering of a hybrid nanoparticle-based nicotine nanovaccine as a next-generation immunotherapeutic strategy against nicotine addiction: a focus on hapten density

Although vaccination is a promising way to combat nicotine addiction, most traditional hapten-protein conjugate nicotine vaccines only show limited efficacy due to their poor recognition and uptake by immune cells. This study aimed to develop a hybrid nanoparticle-based nicotine vaccine with improve...

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Udgivet i:Biomaterials
Main Authors: Zhao, Zongmin, Powers, Kristen, Hu, Yun, Raleigh, Michael, Pentel, Paul, Zhang, Chenming
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344186/
https://ncbi.nlm.nih.gov/pubmed/28167389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2017.01.038
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