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A nanoparticle-based nicotine vaccine and the influence of particle size on its immunogenicity and efficacy

Traditional hapten-protein conjugate nicotine vaccines have shown less than desired immunological efficacy due to their poor recognition and internalization by immune cells. We developed a novel lipid-polymeric hybrid nanoparticle-based nicotine vaccine to enhance the immunogenicity of the conjugate...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nanomedicine
Päätekijät: Zhao, Zongmin, Hu, Yun, Hoerle, Reece, Devine, Meaghan, Raleigh, Michael, Pentel, Paul, Zhang, Chenming
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5298946/
https://ncbi.nlm.nih.gov/pubmed/27520729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2016.07.015
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