Hybrid nanoparticle-based nicotine nanovaccines: Boosting the immunological efficacy by conjugation of potent carrier proteins

A series of hybrid nanoparticle-based nicotine nanovaccines (NanoNicVac) were engineered in this work by conjugating potent carrier protein candidates (Keyhole limpet hemocyanin (KLH) multimer, KLH subunit, cross-reactive material 197 (CRM(197)), or tetanus toxoid (TT)) for enhanced immunological ef...

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Detalhes bibliográficos
Publicado no:Nanomedicine
Main Authors: Zhao, Zongmin, Hu, Yun, Harmon, Theresa, Pentel, Paul R., Ehrich, Marion, Zhang, Chenming
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7262794/
https://ncbi.nlm.nih.gov/pubmed/29719216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2018.04.016
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