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Rational incorporation of molecular adjuvants into a hybrid nanoparticle-based nicotine vaccine for immunotherapy against nicotine addiction

Current clinically-tested nicotine vaccines have yet shown enhanced smoking cessation efficacy due to their low immunogenicity. Achieving a sufficiently high immunogenicity is a necessity for establishing a clinically-viable nicotine vaccine. This study aims to facilitate the immunogenicity of a hyb...

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Pubblicato in:Biomaterials
Autori principali: Zhao, Zongmin, Harris, Brian, Hu, Yun, Harmon, Theresa, Pentel, Paul R., Ehrich, Marion, Zhang, Chenming
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738287/
https://ncbi.nlm.nih.gov/pubmed/29179132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2017.11.021
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